Bring the power of Absolute Q® to your research
Digital PCR can empower a variety of applications. Find yours and see what the Absolute Q can do for you!
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Testing Wastewater Samples for SARS-CoV-2 Using the Absolute Q
Screening wastewater, or sewage, for the presence of SARS-CoV-2 viral RNA can be an effective orthogonal monitoring method in addition to ongoing clinical testing. Wastewater serves as pooled samples from members of a community and enables broad collection of surveillance data.
Using Digital PCR for Optimization of SARS-CoV-2 RNA Extraction Protocol
RNA extraction is a critical step in COVID-19 molecular testing. The loss of viral RNA during the extraction step can result in false negatives. Therefore, optimization of the RNA extraction protocol to ensure consistent and high yield recovery of viral RNA could potentially improve COVID-19 testing accuracy.
4-Color Discrimination of Multi-Allele Single Nucleotide Polymorphisms on the Absolute Q
In this application note created in collaboration with Integrated DNA Technologies, we demonstrate 4-color optical multiplexing for multi-allele single nucleotide polymorphism discrimination.
Evaluation of CRISPR-Cas9 Mediated Genome Edits with the Absolute Q Digital PCR platform
CRISPR-Cas 9 technology has been rapidly adopted due to its ability to make precise edits in the genome. Here, we demonstrate using the Absolute Q to accurately identify both knock-ins and knock-outs.
Testing qPCR positive, negative and inconclusive COVID-19 clinical samples using digital PCR
In this study we tested nucleic acids extracted from 19 clinical specimens using the Absolute Q to demonstrate the improved sensitivity and accuracy of RT-dPCR over traditional RT-qPCR.
|Q| SARS-CoV-2 Triplex Assay: Multiplexed 1-step RT-dPCR for Accurate Viral Target Detection
Leveraging the Absolute Q’s qPCR-like workflow, we showcase the multiplexed 1-step |Q| SARS-CoV-2 RT-dPCR assay by quantifying viral target input with high accuracy down to 5 copies per reaction.
Rare Allele Detection and Quantification Using IDT rhAmp SNP Genotyping System
Integrated DNA Technologies’ rhAMP SNP Genotyping System enables the interrogation of SNPs with high precision. Here, we showcase the first demonstration of an rhAmp assay on a digital PCR platform.
Precise BCR-ABL1 Quantification for Chronic Myeloid Leukemia (CML) Monitoring
Monitoring of the BCR-ABL1 fusion gene is integral to successful TKI treatment in Chronic Myeloid Leukemia. See how the Absolute Q provides accurate measurement of the BCR-ABL1/ABL1 ratio.
4-color Copy Number Variation (CNV) Assay for Spinal Muscular Atrophy (SMA) Screening
Spinal muscular atrophy (SMA) is a leading genetic cause of infant mortality. Here, we describe a 4-plex digital PCR assay capable of quantifying the copy numbers of SMN1 and SMN2 genes, which are central to SMA.
