Quadruplex Absolute Q Digital PCR for Spinal Muscular Atrophy (SMA) Screening
Spinal muscular atrophy (SMA), a genetic neuromuscular disorder and leading genetic cause of infant mortality. Here we describe a 4-color multiplexing digital PCR solution on the COMBiNATi Absolute Q to meet the growing demand for rapid SMA newborn screening and treatment.
Combinati believes simplicity shouldn’t require sacrificing robustness, quality, or rigor – in fact, it should enable it. Our easy-to-use digital PCR platform offers absolute quantification to track disease-relevant biomarkers over time with high accuracy and precision. Our core microfluidic technology, single instrument, and single consumable together enable consistent partitioning of samples with minimal sample waste.
Combined with the ability to robustly reject false positives and easily adapt traditional qPCR assays, Combinati aims to democratize digital PCR for researchers all over the world.
For research use only. Not for use in diagnostic procedures.