Learn how the Absolute Q® can help answer your questions

Our resources below can help you learn how a more accurate dPCR solution can advance your research.

Learn about the Absolute Q Digital PCR Platform

On Demand Learning Center

Learn from experts how digital PCR is redefining nucleic acid quantification and being leveraged to answer complex scientific questions.

Application Notes

See how the Absolute Q dPCR platform has been used for a number of applications.

Infectious Disease

Testing Wastewater Samples for SARS-CoV-2 Using the Absolute Q

Screening wastewater, or sewage, for the presence of SARS-CoV-2 viral RNA can be an effective orthogonal monitoring method in addition to ongoing clinical testing. Wastewater serves as pooled samples from members of a community and enables broad collection of surveillance data.

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Infectious Disease

Using Digital PCR for Optimization of SARS-CoV-2 RNA Extraction Protocol

RNA extraction is a critical step in COVID-19 molecular testing. The loss of viral RNA during the extraction step can result in false negatives. Therefore, optimization of the RNA extraction protocol to ensure consistent and high yield recovery of viral RNA could potentially improve COVID-19 testing accuracy.

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Oncology

4-Color Discrimination of Multi-Allele Single Nucleotide Polymorphisms on the Absolute Q

In this application note created in collaboration with Integrated DNA Technologies, we demonstrate 4-color optical multiplexing for multi-allele single nucleotide polymorphism discrimination.

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Posters and Publications

Combinati’s technology has been featured in posters at renowned conferences as well as published in various scientific journals.

Technical Notes

Learn about the Absolute Q’s technical capabilities and see how microfluidic array partitioning technology can have an impact on your research efforts.

Establishing the Limit of Detection for the |Q| SARS-CoV-2 Triplex Assay

In this study, we characterize the LoD of the Combinati |Q| SARS-CoV-2 RT-dPCR Triplex Kit by diluting reference materials into a pooled negative matrix to determine the lowest concentration at which the assay can reliably identify the sample as containing SARS-CoV-2 targets.

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1-Step Reverse Transcription Digital PCR (RT-dPCR) in Under 2 Hours

Reverse transcription allows the detection and quantification of RNA. Here, we demonstrate a true 1-step RT-dPCR workflow on the Absolute Q by quantifying SARS-CoV-2 targets in under 90 minutes.

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MAP16 dPCR Plate Flexibility: Iterative Assay Optimization Using a Single Plate

The unique architecture of the Absolute Q and the MAP16 allows flexibility that is not offered by any other dPCR platform. See how assay optimization can be done efficiently using a single consumable.

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Applied Biosystems™ TaqMan® Liquid Biopsy Assays for Rare Target Quantification

Read about how the Applied Biosystems™ TaqMan® Liquid Biopsy dPCR assays were used to detect 5 hot-spot cancer mutations on the Combinati Absolute Q platform.

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Customer Testimonials

What our customers have to say.