Learn how the Absolute Q® can help answer your questions

Our resources below can help you learn how a more accurate dPCR solution can advance your research.

Learn about the Absolute Q Digital PCR Platform

On Demand Learning Center

Learn from experts how digital PCR is redefining nucleic acid quantification and being leveraged to answer complex scientific questions.

Application Notes

See how the Absolute Q dPCR platform has been used for a number of applications.

Oncology

Rare Allele Detection and Quantification Using IDT rhAmp SNP Genotyping System

Integrated DNA Technologies’ rhAMP SNP Genotyping System enables the interrogation of SNPs with high precision. Here, we showcase the first demonstration of an rhAmp assay on a digital PCR platform.

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Oncology

Precise BCR-ABL1 Quantification for Chronic Myeloid Leukemia (CML) Monitoring

Monitoring of the BCR-ABL1 fusion gene is integral to successful TKI treatment in Chronic Myeloid Leukemia. See how the Absolute Q provides accurate measurement of the BCR-ABL1/ABL1 ratio.

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Reproductive Health

4-color Copy Number Variation (CNV) Assay for Spinal Muscular Atrophy (SMA) Screening

Spinal muscular atrophy (SMA) is a leading genetic cause of infant mortality. Here, we describe a 4-plex digital PCR assay capable of quantifying the copy numbers of SMN1 and SMN2 genes, which are central to SMA.

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Posters and Publications

Combinati’s technology has been featured in posters at renowned conferences as well as published in various scientific journals.

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Technical Notes

Learn about the Absolute Q’s technical capabilities and see how microfluidic array partitioning technology can have an impact on your research efforts.

Establishing the Limit of Detection for the |Q| SARS-CoV-2 Triplex Assay

In this study, we characterize the LoD of the Combinati |Q| SARS-CoV-2 RT-dPCR Triplex Kit by diluting reference materials into a pooled negative matrix to determine the lowest concentration at which the assay can reliably identify the sample as containing SARS-CoV-2 targets.

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1-Step Reverse Transcription Digital PCR (RT-dPCR) in Under 2 Hours

Reverse transcription allows the detection and quantification of RNA. Here, we demonstrate a true 1-step RT-dPCR workflow on the Absolute Q by quantifying SARS-CoV-2 targets in under 90 minutes.

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MAP16 dPCR Plate Flexibility: Iterative Assay Optimization Using a Single Plate

The unique architecture of the Absolute Q and the MAP16 allows flexibility that is not offered by any other dPCR platform. See how assay optimization can be done efficiently using a single consumable.

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Applied Biosystems™ TaqMan® Liquid Biopsy Assays for Rare Target Quantification

Read about how the Applied Biosystems™ TaqMan® Liquid Biopsy dPCR assays were used to detect 5 hot-spot cancer mutations on the Combinati Absolute Q platform.

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Customer Testimonials

What our customers have to say.